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| Status |
Public on Feb 20, 2008 |
| Title |
Expression data of bronchoalveolar lavage cells from control or urethane treated AJ mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
AJ mouse is susceptible to lung carcinogenesis from urethane treatment and is a good model for human adenocarcinoma. We completed a study using microarray analysis of bronchoalveolar lavage cells from control or urethane treated mice. A unique macrophage expression signature in the lung tumor microenvironment was able to correctly classify the lavage samples.
Keywords: AJ mouse control and urethane treatment carcinogenesis protocol
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| Overall design |
RNA from bronchoalveolar lavage cells of age matched untreated AJ mice controls (C) or from urethane treated (T) AJ mice was prepared. Datasets were accurately classified using a unique macrophage gene expression signature derived from the tumor microenvironment.
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| Contributor(s) |
Stearman RS, Nield LD, Grady MC, Malkinson AM, Geraci MW |
| Citation(s) |
18172294 |
| Submission date |
Mar 13, 2007 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Robert S Stearman |
| E-mail(s) |
Robert.Stearman@uchsc.edu
|
| Phone |
303-315-2317
|
| Fax |
303-315-5632
|
| Organization name |
UCHSC
|
| Department |
Medicine/Pulmonary
|
| Lab |
Stearman
|
| Street address |
4200 E Ninth Ave
|
| City |
Denver |
| State/province |
CO |
| ZIP/Postal code |
80262 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (17)
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| This SubSeries is part of SuperSeries: |
| GSE7269 |
AJ mouse lung carcinogenesis study |
|
| Relations |
| BioProject |
PRJNA104071 |
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