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| Status |
Public on Oct 30, 2007 |
| Title |
Sex differences in gene expression profiles during hantavirus infection of rats |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Gene expression profiles were examined in whole lung tissue collected from male and female Long-Evans rats at different time points after inoculation with Seoul virus (i.e., the species-specific hantavirus that infects Norway rats)
We used microarray analyses to analyze global gene expression differences between the sexes during hantavirus infection
Keywords: time course
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| Overall design |
Gonadally-intact male and female rats were inoculated with 10^4 pfu of Seoul virus (strain SR-11) and lung samples were collected 0, 3, 15, and 40 days post-inoculation (p.i.) to assess gene expression patterns during the acute (i.e., days 3-15 p.i.) and persistent (i.e., day 40 p.i.) phases of infection
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| Contributor(s) |
Klein SL |
| Citation(s) |
18053684 |
| Submission date |
Mar 14, 2007 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Sabra Lynn Klein |
| E-mail(s) |
saklein@jhsph.edu
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| Phone |
(410) 955-8898
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| Fax |
(410) 955-0105
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| Organization name |
Johns Hopkins Bloomberg School of Public Health
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| Department |
Molecular Microbiology and Immunology
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| Lab |
Lab of Sabra Klein
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| Street address |
615 North Wolfe Street
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| City |
Baltimore |
| State/province |
MD |
| ZIP/Postal code |
21205 |
| Country |
USA |
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| Platforms (1) |
| GPL341 |
[RAE230A] Affymetrix Rat Expression 230A Array |
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| Samples (24)
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| GSM175443 |
Female lung, infected, 3 days p.i. (rep1) |
| GSM175444 |
Female lung, infected, 3 days p.i. (rep2) |
| GSM175445 |
Female lung, infected, 3 days p.i. (rep3) |
| GSM175446 |
Female lung, infected, 15 days p.i. (rep1) |
| GSM175447 |
Female lung, infected, 15 days p.i. (rep2) |
| GSM175448 |
Female lung, infected, 15 days p.i. (rep3) |
| GSM175449 |
Female lung, infected, 40 days p.i. (rep1) |
| GSM175450 |
Female lung, infected, 40 days p.i. (rep2) |
| GSM175451 |
Female lung, infected, 40 days p.i. (rep3) |
| GSM175452 |
Male lung, uninfected (rep1) |
| GSM175453 |
Male lung, uninfected (rep2) |
| GSM175454 |
Male lung, uninfected (rep3) |
| GSM175455 |
Male lung, infected, 3 days p.i. (rep1) |
| GSM175456 |
Male lung, infected, 3 days p.i. (rep2) |
| GSM175457 |
Male lung, infected, 3 days p.i. (rep3) |
| GSM175458 |
Male lung, infected, 15 days p.i. (rep1) |
| GSM175459 |
Male lung, infected, 15 days p.i. (rep2) |
| GSM175460 |
Male lung, infected, 15 days p.i. (rep3) |
| GSM175461 |
Male lung, infected, 40 days p.i. (rep1) |
| GSM175462 |
Male lung, infected, 40 days p.i. (rep2) |
| GSM175463 |
Male lung, infected, 40 days p.i. (rep3) |
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| Relations |
| BioProject |
PRJNA97989 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE7271_RAW.tar |
36.8 Mb |
(http)(custom) |
TAR (of CEL) |
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