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Status |
Public on Feb 04, 2016 |
Title |
Aberrant epigenetic regulation in clear cell sarcoma of the kidney (CCSK) |
Organism |
Homo sapiens |
Experiment type |
Methylation profiling by array
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Summary |
Methylation array analyses of 30 CCSKs in comparison with 18 Wilms tumours and normal non-malignant kidneys (2 foetal kidneys and 6 adult kidneys) revealed CCSK tumour DNA to be globally hypermethylated. Four CCSKs, two WTs, two foetal kidneys and 2 adult kidneys were analysed as technical duplicates on different arrays.
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Overall design |
Bisulphite converted DNA was hybridised to the Illumina Infinium HumanMethylation27k array at the SCIBLU Lund University Sweden (http://www.lth.se/sciblu). The samples were analysed on three different arrays.
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Contributor(s) |
Karlsson J, Valind A, Jansson C, O’Sullivan MJ, Holmquist Mengelbier L, Gisselsson D |
Citation(s) |
26848979 |
Submission date |
Sep 18, 2015 |
Last update date |
May 09, 2016 |
Contact name |
Jenny Karlsson |
E-mail(s) |
jenny.karlsson@med.lu.se
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Organization name |
Lund University
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Department |
Clinical genetics
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Street address |
BMC C13
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City |
Lund |
ZIP/Postal code |
SE 221 84 |
Country |
Sweden |
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Platforms (1) |
GPL8490 |
Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2) |
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Samples (66)
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Relations |
BioProject |
PRJNA296327 |