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| Status |
Public on Sep 23, 2015 |
| Title |
Melanoma cell line-induced MDSC transcriptome analysis reveals a unique gene expression profile that is largely reversed to normal monocyte level by MIF inhibition |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Affymetrix microaaray analysis of healthy donor monocytes cultured for 64 hours in the absence of (culture monocytes), or presence of A375 cells (A375-MDSC) or treated with MIF inihibitor, 4-IPP (MDSC+4-IPP; 100mM, day 0 and 50mM, day 2).
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| Overall design |
Significantly modulated genes were clustered into a hierarchical representation. Each column represents one replicate, whereas each row corresponds to the expression of a particular gene across different replicates/experimental conditions.
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| Contributor(s) |
Yaddanapudi K |
| Citation(s) |
26603621, 26981417 |
| Submission date |
Sep 22, 2015 |
| Last update date |
Aug 23, 2018 |
| Contact name |
Kavitha Yaddanapudi |
| E-mail(s) |
k0yadd01@louisville.edu
|
| Phone |
502-852-8643
|
| Organization name |
University of Louisville
|
| Department |
Medicine
|
| Street address |
505 South Hancock Street
|
| City |
Louisville |
| State/province |
KY |
| ZIP/Postal code |
40202 |
| Country |
USA |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA296690 |
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