|
| Status |
Public on Sep 30, 2016 |
| Title |
The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity [FAIRE-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Identification of nucleosome-free, active regulatory regions in in vitro generated CSCs, following the knockdown of the histone linker H1.0
|
| |
|
| Overall design |
FAIRE-seq analysis of biological replicates from SSEA1+ in vitro transformed human skin fibroblasts in the presence or absence of H1.0
|
| |
|
| Contributor(s) |
Morales Torres C, Biran A, Burney MJ, Patel H, Henser-Brownhill T, Hashahar A, Li Y, Nye E, Spencer-Dene B, Ben Hamo R, Efroni S, Matthews N, Misteli T, Meshorer E, Scaffidi P |
| Citation(s) |
27708074 |
| Submission date |
Sep 30, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Paola Scaffidi |
| E-mail(s) |
paola.scaffidi@crick.ac.uk
|
| Organization name |
Francis Crick Institute
|
| Lab |
Cancer Epigenetics Laboratory
|
| Street address |
1 Midland Road
|
| City |
London |
| ZIP/Postal code |
NW1 1AT |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (12)
|
| GSM1898779 |
shH1.0-1 Input biological replicate 1 [FAIRE-Seq] |
| GSM1898780 |
shH1.0-1 NT biological replicate 1 [FAIRE-Seq] |
| GSM1898781 |
shH1.0-1 DOX biological replicate 1 [FAIRE-Seq] |
| GSM1898782 |
shH1.0-1 Input biological replicate 2 [FAIRE-Seq] |
| GSM1898783 |
shH1.0-1 NT biological replicate 2 [FAIRE-Seq] |
| GSM1898784 |
shH1.0-1 DOX biological replicate 2 [FAIRE-Seq] |
| GSM1898785 |
shH1.0-2 Input biological replicate 1 [FAIRE-Seq] |
| GSM1898786 |
shH1.0-2 NT biological replicate 1 [FAIRE-Seq] |
| GSM1898787 |
shH1.0-2 DOX biological replicate 1 [FAIRE-Seq] |
| GSM1898788 |
shH1.0-2 Input biological replicate 2 [FAIRE-Seq] |
| GSM1898789 |
shH1.0-2 NT biological replicate 2 [FAIRE-Seq] |
| GSM1898790 |
shH1.0-2 DOX biological replicate 2 [FAIRE-Seq] |
|
| This SubSeries is part of SuperSeries: |
| GSE65520 |
Dynamic regulation of the histone variant H1.0 contributes to intratumor epigenetic and functional heterogeneity |
|
| Relations |
| BioProject |
PRJNA297413 |
| SRA |
SRP064343 |
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