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| Status |
Public on Feb 05, 2016 |
| Title |
miRNA expression in the canalicular phase of human lung development |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
MicroRNA expression levels were assessed during the canalicular phase of normal fetal lung development at the critical time, when the distal airway epithelium proliferates and differentiates. Precise miRNA regulation is important for proper pulmonary organogenesis, supporting the delicate balance between expansion of progenitor cells and their terminal differentiation. Microarray analyses could indicate the potential involvement of miRNAs important for human pulmonary hypoplasia.
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| Overall design |
Two replicates of pooled RNA from two 18-20 week old fetal lung samples
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| Contributor(s) |
Sanford EL, Choy K, Loscertales M, Longoni M |
| Citation(s) |
26891231 |
| Submission date |
Jan 15, 2016 |
| Last update date |
May 09, 2016 |
| Contact name |
Mauro Longoni |
| Organization name |
Massachusetts General Hospital
|
| Department |
Pediatric Surgical Research Laboratories
|
| Street address |
185 Cambridge Street
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02114 |
| Country |
USA |
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| Platforms (1) |
| GPL8227 |
Agilent-019118 Human miRNA Microarray 2.0 G4470B (miRNA ID version) |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE76921 |
microRNA expression levels during the pseudoglandular to canalicular phase transition of fetal lung development |
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| Relations |
| BioProject |
PRJNA308937 |
