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| Status |
Public on Jun 15, 2020 |
| Title |
Gene expression profiles in fetal human liver sinusoidal endothelial cells (LSEC) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Understanding molecular fingerprints of specific cell types is central for defining lineage development, progression, differentiation and pathophysiological perturbations. This study addressed gene expression profiles in freshly isolated fetal human LSEC as well as these LSEC after cell culture.
Comparisons with human umbilical vein endothelial cells (HUVEC) allowed determination of lineage-specific differences. Cell culture allowed identification of differences in phenotype regulation of cells under these conditions.
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| Overall design |
Comparisons were made between freshly isolated LSEC (PP cells), LSEC after initial culture (P0 cells) and LSEC after passages (P2 or P3) from 3 donors each. Freshly isolated HUVEC served as controls for comparisons.
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| Contributor(s) |
Bandi S, Tchaikovskaya T, Gupta S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jan 27, 2016 |
| Last update date |
Jun 16, 2020 |
| Contact name |
Sanjeev Gupta |
| E-mail(s) |
sanjeev.gupta@einsteinmed.org
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| Organization name |
Albert Einstein College of Medicine
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| Department |
Medicine
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| Street address |
1300 Morris Park Ave.
|
| City |
Bronx |
| State/province |
NY |
| ZIP/Postal code |
10461 |
| Country |
USA |
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| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA309984 |
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