|
| Status |
Public on Feb 06, 2016 |
| Title |
Combination of multiomics approach and BCR-ABL based molecular testing: A better way to monitor treatment regimen and disease progression in Chronic Myeloid Leukemia [OncoScan] |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by SNP array
|
| Summary |
We screened TKI-treated-CML-samples in different-phases based on < or >10% copies of BCR-ABL, undetected and control-samples for generating transcriptomics-profile.
Transcriptionally, three clusters were identified which showed correlation with BCR-ABL transcript-levels i.e. <10% copies (I-cluster) , undetectable (II-cluster) and >10% copies (III-cluster).
|
| |
|
| Overall design |
CML-new cases as well as Tyrosiine kinase treated-different phases of CML
|
| |
|
| Contributor(s) |
Singh N, Tripathi AK, sahu DK, Mishra A, Chowdhry R, Kant R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Feb 04, 2016 |
| Last update date |
Feb 07, 2016 |
| Contact name |
Neetu Singh |
| E-mail(s) |
neetuaashi@yahoo.com
|
| Phone |
9984801444
|
| Organization name |
King George's Medical University
|
| Department |
Center for Advance Research
|
| Street address |
Chowk
|
| City |
Lucknow |
| ZIP/Postal code |
226003 |
| Country |
India |
| |
|
| Platforms (1) |
| GPL18602 |
[OncoScan] Affymetrix OncoScan FFPE Assay |
|
| Samples (39)
|
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| This SubSeries is part of SuperSeries: |
| GSE77573 |
Combination of multiomics approach and BCR-ABL based molecular testing: A better way to monitor treatment regimen and disease progression in Chronic Myeloid Leukemia |
|
| Relations |
| BioProject |
PRJNA310987 |
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