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| Status |
Public on Mar 08, 2017 |
| Title |
Expression data of differentially regualted genes in TH-MYCN mouse tumors after immunotherapy |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
In order to understand differentially regulated gene expression after the different treatments, 4 size matched tumors of each group were analyzed by microarrays.
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| Overall design |
TH-MYCN mice were treaded for 10 days with BLZ945 (CSF-1R inhibitor, Novartis), anti-PD-1/L1 antibodies, are the combination of both. Control mice remained untreated.
Heterozyous TH-MYCN mice were treated for 10 days as soon as they had a palpable tumor in their abdomen. At day 10, mice were sacrificed, tumors were weighed and snap frozen. Tumors were kept at -80degree until further analysis.
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| Contributor(s) |
Eissler N, Kogner P |
| Citation(s) |
28123870 |
| Submission date |
Mar 22, 2016 |
| Last update date |
Mar 08, 2018 |
| Contact name |
Per Kogner |
| Organization name |
Karolinska Institutet
|
| Department |
Department of Women´s and Children´s Health
|
| Lab |
Per Kogner, Childhood Cancer Research Unit
|
| Street address |
Karolinska University Hospital
|
| City |
Stockholm |
| ZIP/Postal code |
17176 |
| Country |
Sweden |
| |
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| Platforms (1) |
| GPL17400 |
[MoGene-2_1-st] Affymetrix Mouse Gene 2.1 ST Array [transcript (gene) version] |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA315972 |
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