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| Status |
Public on Jul 31, 2016 |
| Title |
Prox1 (Prosper-related homeobox 1) transcription factor depletion effect on CGTH-W-1 cells. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Analysis of CGTH-W-1 follicular thyroid carcinoma cells transcriptome following 48 hrs siRNA-mediated depletion of PROX1. PROX1 is a homeobox transcription factor. PROX1 depletion decreases migratory ability, motility and invasivness and induces profound cytoskeleton changes of CGTH-W-1 cells. Results provide insight into the role of PROX1 in the thyroid cancer.
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| Overall design |
Three biological replicates for a given condition
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| Contributor(s) |
Rudzińska M, Ledwoń J, Sikorska J, Paczkowska K, Paziewska A, Mikula M, Ostrowski J, Czarnocka B |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 11, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Katarzyna Paczkowska |
| E-mail(s) |
paczkowska.km@gmail.com
|
| Organization name |
Cancer Center - Institute
|
| Department |
Department of Genetics
|
| Street address |
Roentgena 5
|
| City |
Warsaw |
| ZIP/Postal code |
02-781 |
| Country |
Poland |
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| Platforms (1) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA318015 |
| SRA |
SRP073100 |
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