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| Status |
Public on Oct 27, 2016 |
| Title |
Identification of miR-210 target genes in T20 patient-derived sphere culture |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Hypoxia is known to regulate tumor-initiating cells and to have an effect on miRNA expression. We were interested in studying the role of hypoxia-induced miR-210 in colorectal cancer patient-derived sphere cultures.
Downregulated genes after overexpression of miR-210 were retained as potential miR-210 target genes for further validation sudies.
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| |
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| Overall design |
Colorectal cancer patient-derived (patient name: T20) sphere cultures were stably transduced with miR-210 lentiviral particles (Biosettia) or control vectors, respectively. Three technical replicates were used for both conditions.
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| |
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| Citation(s) |
27589845 |
| Submission date |
Apr 13, 2016 |
| Last update date |
Mar 15, 2019 |
| Contact name |
Elisabeth Letellier |
| E-mail(s) |
elisabeth.letellier@uni.lu
|
| Organization name |
University of Luxembourg
|
| Department |
Life Sciences Research Unit
|
| Lab |
Molecular Disease Mechanisms
|
| Street address |
6, Avenue du Swing
|
| City |
Belvaux |
| ZIP/Postal code |
L-4367 |
| Country |
Luxembourg |
| |
|
| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
|
| Samples (6)
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| Relations |
| BioProject |
PRJNA318377 |
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