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| Status |
Public on Feb 08, 2017 |
| Title |
Gene expression alternations in the offspring liver from chromium restriction diet dams |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Maternal chromium restriction may disturb susceptibility in offspring. Liver from maternal chromium diet has 264 up- and 199 down- regulated genes, compared to control. Especially, Insulin signaling pathway and WNT pathway were affected.
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| |
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| Overall design |
We performed microarray analyses of offspring liver from chromium restriction dams and control diet dams at 32 week (n=3 per group).
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| Contributor(s) |
Zhang Q, Sun X, Xiao X, Zheng J, Li M, Yu M, Ping F, Wang Z, Qi C, Wang T, Wang X |
| Citation(s) |
27782077 |
| Submission date |
May 30, 2016 |
| Last update date |
Feb 21, 2018 |
| Contact name |
Qian Zhang |
| Organization name |
Peking Union Medical College Hospital
|
| Street address |
No. 1 Shuaifuyuan, Dongcheng District
|
| City |
Beijing |
| ZIP/Postal code |
100730 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (6)
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| GSM2181568 |
Liver_maternal chromium restriction diet_32week_rep1 |
| GSM2181569 |
Liver_maternal chromium restriction diet_32week_rep2 |
| GSM2181570 |
Liver_maternal chromium restriction diet_32week_rep3 |
|
| Relations |
| BioProject |
PRJNA323721 |
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