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| Status |
Public on Dec 30, 2017 |
| Title |
Cell type-specific regulation by intragenic CpG islands [WGBS] |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
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| Summary |
We wanted to emphisize the role of intragenic CpG island in various cell differentiation. We especially examined the effect of DNA methyltransferase (DNMT) in the neural differentiation from mouse ES cell. Therefore, we performed the Whole-Genome Bisulfite Sequencing (WGBS) analysis of mouse ES cell, ESC-derived NPC, and also in DNMT double knockout (DKO) conditions. By utilizing these result, we confirmed the genes regulated by intragenic CpG island methylation have effect in NPC differentation.
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| Overall design |
4 WGBS data from mouse ES cell, mouse ES cell-derived NPC, DNMT3A/B DKO mouse ES cell, and DNMT3A/B DKO mouse ES cell-derived NPC
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| Contributor(s) |
Lee S, Noh K, Lee J |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| BioProject |
PRJNA319411 |
| Submission date |
Jun 01, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Jungwoo Lee |
| E-mail(s) |
ljw90607@hotmail.com
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| Organization name |
Yonsei University
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| Lab |
GRC
|
| Street address |
50 Yonsei-ro Seodaemun-gu
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| City |
Seoul |
| ZIP/Postal code |
120-749 |
| Country |
South Korea |
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| Platforms (1) |
| GPL9185 |
Illumina Genome Analyzer (Mus musculus) |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE82142 |
Cell type-specific regulation by intragenic CpG islands |
|
| Relations |
| SRA |
SRP075981 |
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