|
| Status |
Public on Jun 10, 2016 |
| Title |
Lead Modulates trans- and cis-eQTLs in Drosophila melanogaster Heads |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goal was to study the effects of lead exposure on gene expression and identify the lead-responsive genes. After detecting 1,536 cis-eQTLs (FDR ≤ 10%) and 952 trans-eQTLs, we focused our analysis on Pb-sensitive “trans-eQTL hotspots”.
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| |
|
| Overall design |
158 randomly selected Drosophila Synthetic Population Resource (A2) samples (control 79 samples and Pb-treated) without replicates
|
| |
|
| Contributor(s) |
Qu W, Ruden DM |
| Citation(s) |
30294342, 29114259 |
| Submission date |
Jun 09, 2016 |
| Last update date |
May 24, 2019 |
| Contact name |
Wen Qu |
| E-mail(s) |
er7989@wayne.edu
|
| Organization name |
Wayne State University
|
| Department |
Pharmacology
|
| Lab |
Douglas Ruden
|
| Street address |
275 E. Hancock Ave., Room 291.1
|
| City |
Detroit |
| State/province |
MI |
| ZIP/Postal code |
48201 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13304 |
Illumina HiSeq 2000 (Drosophila melanogaster) |
|
| Samples (158)
|
|
| Relations |
| BioProject |
PRJNA325107 |
| SRA |
SRP076333 |
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