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Series GSE83374 Query DataSets for GSE83374
Status Public on Sep 30, 2016
Title Gene expression data from iPSC-derived astrocytes, comparison
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Alexander disease (AxD) is a fatal neurological illness characterized by white-matter degeneration and formation of Rosenthal fibers, which contain glial fibrillary acidic protein (GFAP) as astrocytic inclusion. AxD is mainly caused by a gene mutation encoding GFAP, although the underlying pathomechanism remains unclear.
 
Overall design We differentiated human iPSCs into astrocytes and analyzed gene expression profiles of control and the AxD astrocytes. Comparison between control (n=3) and AxD (n=1)
 
Contributor(s) Inoue H, Kondo T
Citation(s) 27402089
Submission date Jun 15, 2016
Last update date Mar 15, 2019
Contact name Haruhisa Inoue
E-mail(s) haruhisa@cira.kyoto-u.ac.jp
Phone +81-75-366-7036
Organization name Kyoto University
Street address 53 Kawahara-cho, Shogoin, Sakyo-ku
City Kyoto
State/province Kyoto
ZIP/Postal code 606-8507
Country Japan
 
Platforms (1)
GPL16686 [HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version]
Samples (4)
GSM2200368 iPSC-derived astrocytes from HC1
GSM2200369 iPSC-derived astrocytes from HC2
GSM2200370 iPSC-derived astrocytes from HC3
Relations
BioProject PRJNA325729

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE83374_RAW.tar 26.5 Mb (http)(custom) TAR (of CEL)
GSE83374_disease-associated_matrix.txt.gz 14.0 Kb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record

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