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Status |
Public on Sep 30, 2016 |
Title |
Gene expression data from iPSC-derived astrocytes, comparison |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Alexander disease (AxD) is a fatal neurological illness characterized by white-matter degeneration and formation of Rosenthal fibers, which contain glial fibrillary acidic protein (GFAP) as astrocytic inclusion. AxD is mainly caused by a gene mutation encoding GFAP, although the underlying pathomechanism remains unclear.
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Overall design |
We differentiated human iPSCs into astrocytes and analyzed gene expression profiles of control and the AxD astrocytes. Comparison between control (n=3) and AxD (n=1)
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Contributor(s) |
Inoue H, Kondo T |
Citation(s) |
27402089 |
Submission date |
Jun 15, 2016 |
Last update date |
Mar 15, 2019 |
Contact name |
Haruhisa Inoue |
E-mail(s) |
haruhisa@cira.kyoto-u.ac.jp
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Phone |
+81-75-366-7036
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Organization name |
Kyoto University
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Street address |
53 Kawahara-cho, Shogoin, Sakyo-ku
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City |
Kyoto |
State/province |
Kyoto |
ZIP/Postal code |
606-8507 |
Country |
Japan |
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Platforms (1) |
GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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Samples (4)
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Relations |
BioProject |
PRJNA325729 |