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Series GSE83632 Query DataSets for GSE83632
Status Public on Jul 06, 2016
Title Whole-transcript expression data from normal and DLBCL human peripheral blood samples
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Gene expression profiling based classification of DLBCL patients versus healthy donors provides insights on transcriptional regulation processes.
Within the most represented pathways in DLBCL, we identified an innate immune response signature, as well as an anti-inflammatory response. On the other hand, a significant under-representation of pathways involved in T-cell activation was also revealed.
 
Overall design Whole blood from 76 DLBCL patients and 87 healthy donors was collected into PAXgene Blood RNA tubes (Becton Dickinson BD Biosciences, San Jose, CA, USA) ensuring blood stabilization and stored at -80°C before RNA extraction. Total RNA, after globin mRNA depletion, was hybridized onto Affymetrix GeneChip® Human Exon 1.0 ST oligonucleotide arrays (Affymetrix, Santa Clara, CA, USA) according to manufacturer’s instructions.
 
Contributor(s) Rossille D, Pangault C, Fest T
Citation(s) 27338100
Submission date Jun 22, 2016
Last update date Feb 18, 2019
Contact name Delphine Rossille
E-mail(s) delphine.rossille@univ-rennes1.fr
Organization name INSERM U1236-MOBIDIC
Street address 2 avenue du Pr. Léon Bernard
City Rennes
ZIP/Postal code 35000
Country France
 
Platforms (1)
GPL5175 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version]
Samples (163)
GSM2211431 Blood sample from DLBCL patient, rep 1
GSM2211432 Blood sample from DLBCL patient, rep 2
GSM2211433 Blood sample from DLBCL patient, rep 3
Relations
BioProject PRJNA326532

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE83632_RAW.tar 3.5 Gb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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