|
Status |
Public on Jun 22, 2017 |
Title |
Effect of dimethyl fumarate (DMF) and transforming growth factor (TGFb) on gene expression in dermal fibroblasts |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
|
Summary |
Primary adult dermal fibroblasts isolated from forearm skin biopsy of 3 healthy donors were treated with DMF and TGFb.
|
|
|
Overall design |
3 cell lines of dermal fibroblasts were derived from skin biopses from healthy donors. All cell lines were subjected to 4 treatments: control (DMSO), dimethyl fumarate (DMF), TGFb, and TGFb+DMF. The goal of the study was to identify sets of genes regulated by different treatments.
|
|
|
Contributor(s) |
Grzegorzewska AP, Haines P, Trojanowska M |
Citation(s) |
28870693 |
Submission date |
Jun 23, 2016 |
Last update date |
Aug 01, 2019 |
Contact name |
Boston University Microarray and Sequencing Resource |
E-mail(s) |
msrdata@bu.edu
|
Organization name |
Boston University
|
Department |
Microarray and Sequencing Resource
|
Street address |
72 East Concord Street, E631
|
City |
Boston |
State/province |
MA |
ZIP/Postal code |
02118 |
Country |
USA |
|
|
Platforms (1) |
GPL17930 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [HuGene20stv1_Hs_ENTREZG_17.0.0] |
|
Samples (12)
|
|
Relations |
BioProject |
PRJNA326588 |