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| Status |
Public on Sep 01, 2016 |
| Title |
Expression data from human normal liver cell line HL7702 treated with tributyltin |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Tributyltin (TBT) accumulates at higher levels in the liver than in any other organ, and it acts as a hepatotoxic agent. Most of the available studies on TBT have focused on observations at the cellular level, and studies at the level of genes and proteins have been limited; therefore, the information concerning possible mechanisms of TBT-induced adverse health effects remains scarce and inconclusive.
In the present study, we applied a toxicogenomic approach to investigate the effects of TBT on gene expression in the human normal liver cell line HL7702.
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| Overall design |
The HL7702 cells were treated with 0 μM (C0), 2 μM(C1), 6 μM (C2) and 10 μM (C3) TBT for 2 h, and three biological replicates for each concentration.
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| Contributor(s) |
Zhou M, Feng M, Xu J |
| Citation(s) |
26018654 |
| Submission date |
Aug 31, 2016 |
| Last update date |
Aug 23, 2018 |
| Contact name |
Jin Xu |
| E-mail(s) |
nbusykes@163.com
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| Organization name |
Ningbo University
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| Street address |
818 Fenghua Road
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| City |
Ningbo |
| ZIP/Postal code |
315211 |
| Country |
China |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA341320 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE86259_RAW.tar |
25.4 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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