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| Status |
Public on Feb 04, 2017 |
| Title |
Transcriptome analyses of rhesus monkey pre-implantation embryos reveal a reduced capacity for DNA double strand break (DSB) repair in primate oocytes and early embryos |
| Organism |
Macaca mulatta |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Pre-implantation embryogenesis encompasses several critical events including genome reprogramming, zygotic genome activation (ZGA), and cell fate commitment, of which most remain mechanistically unclear in primate. Here we carried out time-series RNA-seq in 26 single and 8 pooled rhesus monkey oocytes and pre-implantation embryos encompassing representative developmental stages to explore these process.
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| Overall design |
Transcriptome of 8 pooled and 26 single Rhesus Monkey oocytes and preimplantation embryos of stages from germinal vesicle-stage oocytes to blastocyst.
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| |
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| Contributor(s) |
Wang X, Liu D |
| Citation(s) |
28223401 |
| Submission date |
Sep 14, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Denghui Liu |
| E-mail(s) |
liudenghui@gmail.com
|
| Phone |
+86-02154920572
|
| Organization name |
CAS-MPG Partner Institute for Computational Biology (PICB)
|
| Lab |
Jing-Dong Jackie Han's Lab
|
| Street address |
ShengLi Building, 320 Yueyang Road
|
| City |
Shanghai |
| State/province |
Shanghai |
| ZIP/Postal code |
200031 |
| Country |
China |
| |
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| Platforms (2) |
| GPL14954 |
Illumina HiSeq 2000 (Macaca mulatta) |
| GPL19129 |
Illumina HiSeq 2500 (Macaca mulatta) |
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| Samples (34)
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| Relations |
| BioProject |
PRJNA343030 |
| SRA |
SRP089891 |
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