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| Status |
Public on Jun 29, 2017 |
| Title |
Rhinovirus Infection Induces a Differential Gene Expression Pattern in Pulmonary Epithelial Cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We aimed to investigate whether HRV infection induces a specific gene expression pattern in airway epithelial cells.
The study suggests the underlying molecular regulatory networks genes which might be involved in pathogenicity of the HRV-B and potential targets for further validations and development of effective treatment.
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| Overall design |
Human alveolar epithelial cell monolayers were infected with HRV species B (HRV-B). Total RNA was extracted from both supernatants and infected monolayer cells at 6, 12, 24 and 48 hours post infection (hpi) and transcriptional profile was analyzed using high-density oligonucleotide Affymetrix GeneChip and the results were subsequently validated by using quantitative Real-time PCR method.
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| Contributor(s) |
Etemadi M, LING K, Yee CH, Sekawi Z |
| Citation(s) |
28558071 |
| Submission date |
Sep 29, 2016 |
| Last update date |
Aug 23, 2018 |
| Contact name |
Mohammad Reza Etemadi |
| E-mail(s) |
mr_etemadi@yahoo.com
|
| Phone |
0060172197192
|
| Organization name |
UPM
|
| Department |
Medical Microbiology and Parasitology
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| Lab |
Mohammad Reza
|
| Street address |
K17
|
| City |
Serdang |
| State/province |
Selangor |
| ZIP/Postal code |
43400 |
| Country |
Malaysia |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA344854 |
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