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| Status |
Public on Nov 09, 2017 |
| Title |
Whole-transcriptome maps of HepG2 cells after exposure to cationic liposomes and controls |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Cationic liposomes (CLs) are non-viral vectors that play a major role in DNA transfer and gene therapy. The cellular toxicity of CLs has been validated in HepG2 cells. To address the basis of the CLs toxicity, we performed RNA-seq analysis on untreated HepG2 cells and HepG2 cells following exposure to IC50 concentration (120μM) CLs for 24h.
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| |
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| Overall design |
Examination of gene expression level in CLs treated HepG2 cells and untreated cells
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| |
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| Contributor(s) |
Li Y, Chen Q, Zhang H, Yu J, Sun D, Zhang G |
| Citation(s) |
29996945 |
| Submission date |
Nov 09, 2016 |
| Last update date |
Jul 26, 2019 |
| Contact name |
Li Ying |
| E-mail(s) |
cnxxr@126.com
|
| Organization name |
Eastern Hepatobiliary Surgery Hospital
|
| Department |
Department of Pharmacy
|
| Street address |
Changhai Road No. 225
|
| City |
Shanghai |
| ZIP/Postal code |
200438 |
| Country |
China |
| |
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| Platforms (1) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
|
| Samples (6)
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| Relations |
| BioProject |
PRJNA353052 |
| SRA |
SRP093311 |
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