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Series GSE89714 Query DataSets for GSE89714
Status Public on Nov 10, 2016
Title Differential gene expressions in the heart of hypertrophic cardiomyopathy patients
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Differential gene expressions were constructed through expression profiling of a total of 20,127 genes in the heart tissue of hypertrophic cardiomyopathy patients, then 1799 significant differential genes were filtered based on the criteria (p<0.05 and fold change > 1.5), respectively.
Overall design In the study presented here, human hypertrophic heart tissue samples were obtained from patients previously diagnosed with hypertrophic cardiomyopathy, undergoing septal myectomy surgery (n=5). Control samples were obtained from normal heart donor left ventricles (n=4). The heart tissues were collected and performed transcriptome analysis by RNA-sequencing. Compared to normal heart, 1799 significant differentially expressed genes (filtering criteria p<0.05, fold change>1.5) were identified 7-days or 28 days post-Ang II infusion.
Contributor(s) Li Y, Guo H
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Submission date Nov 09, 2016
Last update date Apr 16, 2021
Contact name 李 玉琳
Organization name Beijing Institute of Heart Lung and Blood Vessel Diseases
Street address 2 Anzhen Rd, Chaoyang District,
City Beijing
ZIP/Postal code 100029
Country China
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (9)
GSM2387228 HY1
GSM2387229 HY2
GSM2387230 HY4
BioProject PRJNA352990
SRA SRP093240

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Supplementary file Size Download File type/resource
GSE89714_Annotation.txt.gz 301.6 Kb (ftp)(http) TXT
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Processed data are available on Series record

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