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Status |
Public on Jan 31, 2018 |
Title |
Expression data from patients with HCC receiving Nivolumab |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
|
Summary |
We have generated an immune classifier able to identify patients belonging to the immune subclass of HCC. Characteristics of the immune subclass resemble those of patients who most respond to immunotherapy. We performed microarray expression of the tumors of two patients before starting treatment with nivolumab to verify if the immune classifier generated was able to predict response to immunotherapy.
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Overall design |
Upon patients’ consent, RNA extraction and RNA profiling were performed on tumoral sections derived from available archived tissues collected any time before treatment.
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Contributor(s) |
Sia D |
Citation(s) |
28624577 |
Submission date |
Jan 16, 2017 |
Last update date |
Aug 23, 2018 |
Contact name |
Daniela Sia |
Organization name |
Icahn school of Medicine at Mount Sinai
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Department |
Liver Diseases
|
Street address |
1425 Madison Avenue
|
City |
New York |
ZIP/Postal code |
10029 |
Country |
USA |
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Platforms (1) |
GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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Samples (2) |
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Relations |
BioProject |
PRJNA361457 |