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| Status |
Public on Jun 12, 2017 |
| Title |
Expression data from MCF-7 breast cancer cells treated with Wild Type Tomato fruit extract (WT) and transgenic lines tomato fruit extract (L6 and L7) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To investigate the effects of transgenic lines L6 and L7 tomato fruits on total expression profile of MCF-7 breast cancer cells, we treated MCF-7 cells with 1 ug/ml of tomato fruit extract for 24 hours and compare it with wild type tomato fruit extract
Objectives for this study included the identification of genes that were up or down-regulated at the transcriptional level in MCF-7 cells treated with transgenic lines L6 and L7 tomatofruit extract and compare it to wild type tomato fruit extract.
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| Overall design |
MCF-7 breast cancer cells were incubated with wild type (WT) tomatofruit extract (1 ug/ml), line 6 (L6) transgenic line tomato fruit extract (1 ug/ml) and line 7 (L7) transgenic line tomato fruit extract (1 ug/ml) for 24 hours and selected for RNA extraction and hybridization on Affymetrix microarrays.
cell death responses
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| Contributor(s) |
Khodakovskaya M |
| Citation(s) |
28448505 |
| Submission date |
Feb 06, 2017 |
| Last update date |
Aug 23, 2018 |
| Contact name |
Mariya Khodakovskaya |
| E-mail(s) |
m_khod@yahoo.com
|
| Organization name |
University of Arkansas at Little Rock
|
| Department |
Biology
|
| Street address |
2801 S. University Avenue
|
| City |
Little Rock |
| State/province |
AR |
| ZIP/Postal code |
72204 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
|
| Samples (8)
|
| GSM2478005 |
MCF-7_Treated with WT tomato fruit extract rep.1 |
| GSM2478006 |
MCF-7_Treated with WT tomato fruit extract rep.2 |
| GSM2478007 |
MCF-7_Treated with L7 tomato fruit extract rep.1 |
| GSM2478008 |
MCF-7_Treated with L7 tomato fruit extract rep.2 |
| GSM2478009 |
MCF-7_Treated with L6 tomato fruit extract rep.1 |
| GSM2478010 |
MCF-7_Treated with L6 tomato fruit extract rep.2 |
| GSM2478011 |
MCF-7_negative control (non-treated) rep.1 |
| GSM2478012 |
MCF-7_negative control (non-treated) rep.2 |
|
| Relations |
| BioProject |
PRJNA371453 |
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