|
| Status |
Public on Nov 02, 2007 |
| Title |
An E2F1-Dependent Gene Expression Program That Determines the Balance Between Proliferation and Cell Death |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
E2F1 has been shown to induce both proliferation and apoptosis.
We now show that PI3K/Akt signaling regulates the balance of these events by specifically blocking expression of genes in the E2F1 apoptotic program but not the proliferative program.
Keywords: PI3K dependent modulation of E2F1 gene expression measured by Affymetrix gene expression analysis
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| |
|
| Overall design |
11 samples total, two replicates each (except Sample 1 which is represented once)
|
| |
|
| Contributor(s) |
Hallstrom TC, Mori S, Nevins JR |
| Citation(s) |
18167336 |
| Submission date |
Nov 01, 2007 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Timothy C. Hallstrom |
| E-mail(s) |
halls026@umn.edu
|
| Organization name |
University of Minnesota
|
| Department |
Pediatrics
|
| Street address |
MMC 366
|
| City |
Minneapolis |
| State/province |
MN |
| ZIP/Postal code |
55455 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL341 |
[RAE230A] Affymetrix Rat Expression 230A Array |
|
| Samples (11)
|
|
| Relations |
| BioProject |
PRJNA103283 |
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