|
| Status |
Public on May 04, 2017 |
| Title |
Molecular Mediators of Cardiac Pathology in Cardiorenal Syndrome Type 4 [anti-miR-21] |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report the changes in left ventricle mRNA abundance in response to miR-21-5p suppression in 5/6 nephrectomized rats.
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| Overall design |
Ten week old male Sprague Dawley rats were subjected to the excision model of 5/6 nephrectomy (5/6Nx) surgery. LNA-anti-scrambled or LNA-anti-miR-21-5p was delivered intravenously in 3 daily doses of 1 mg/kg at 1 and 4 weels post-surgery. Left ventricle tissue was collected for mRNA sequencing 7 weeks after surgery.
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| |
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| Contributor(s) |
Chuppa S, Liang M, Liu P, Liu Y, Casati MC, Cowley AW, Patullo L, Kriegel AJ |
| Citation(s) |
28760335 |
| Submission date |
May 03, 2017 |
| Last update date |
Aug 01, 2019 |
| Contact name |
Alison J. Kriegel |
| E-mail(s) |
akriegel@mcw.edu
|
| Phone |
(414)955-4835
|
| Organization name |
Medical College of Wisconsin
|
| Department |
Physiology
|
| Lab |
Kriegel
|
| Street address |
8701 Watertown Plank Rd.
|
| City |
Milwaukee |
| State/province |
WI |
| ZIP/Postal code |
53226 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL14844 |
Illumina HiSeq 2000 (Rattus norvegicus) |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE97950 |
Molecular Mediators of Cardiac Pathology in Cardiorenal Syndrome Type 4 |
|
| Relations |
| BioProject |
PRJNA385371 |
| SRA |
SRP106489 |
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