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Items: 1 to 20 of 601

1.
Full record GDS5658

Retinoid X receptor activation effect on stimulated RAW264.7 cells

Analysis of RAW 264.7 macrophages pre-treated with vitamin A derivative 9cis-retinoic acid (9cRA), then stimulated with bacterial LPS or viral mimetic polyI:C. 9cRA is a high affinity ligand for retinoid X receptor (RXR). Results provide insight into the role of RXR in host antiviral response.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 protocol, 3 stress sets
Platform:
GPL1261
Series:
GSE62107
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5658
ID:
5658

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2.
Full record GDS5656

Forkhead box O 1,3,4 muscle-specific knockout effect on fasted gastrocnemius muscle

Analysis of gastrocnemius muscle from starved males with muscle-specific deletion of Forkhead Box O transcription factors 1, 3 and 4 (FoxO1,3,4-/-). Results provide insight into the collective roles of FoxOs during muscle atrophy.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 stress sets
Platform:
GPL1261
Series:
GSE52667
4 Samples
Download data: CEL
DataSet
Accession:
GDS5656
ID:
5656

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3.
Full record GDS5660

Early postnatal skeletal muscle stem cells: time course

Analysis of myogenic stem cells called satellite cells (mSCs) FACS-sorted from the trunk of Pax3GFP/+ mice at postnatal days 1, 12, and 28, a period when most mSCs are in proliferation and quiescence states. Results provide insight into molecular basis of early postnatal skeletal muscle development.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 age, 2 tissue sets
Platform:
GPL1261
Series:
GSE65927
11 Samples
Download data: CEL
DataSet
Accession:
GDS5660
ID:
5660

PubMed Similar studies GEO Profiles Analyze DataSet

4.
Full record GDS5624

Epigenetic modifying reagents effect on a progressive hearing loss model: whole cochlea

Analysis of cochlea from 4 wk old DBA/2J males (a model of progressive hearing loss) injected for 8 wks with a combination of epigenetic modifiers l-methionine and valproic acid. Results provide insight into the effect of epigenetic modifications on the molecular mechanisms underlying hearing loss.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 age, 3 protocol sets
Platform:
GPL1261
Series:
GSE62173
16 Samples
Download data: CEL
DataSet
Accession:
GDS5624
ID:
5624

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5.
Full record GDS5663

Pulmonary dendritic cell subsets

Analysis of four dendritic cell (DC) subsets purified from the lungs of C57BL/6 males following inhalation of LPS/OVA. The four subsets represent conventional DCs (cDCs) and monocyte-derived DCs (moDCs). Results provide insight into molecular profiles that would discriminate between cDCs and moDCs.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 cell type, 2 other sets
Platform:
GPL1261
Series:
GSE64896
12 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5663
ID:
5663

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6.
Full record GDS5813

Bone morphogenetic protein 4 and forskolin effect on embryonic AGM VE-cadherin+ cells

Analysis of vascular endothelial (VE)-cadherin+ cells isolated from aorta-gonad-mesonephros (AGM) region of E11.5 embryos then treated with bone morphogenetic protein (BMP) 4, adenylyl cyclase activator forskolin, or both. Results provide insight into the role of BMP signaling in AGM hematopoiesis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 4 agent sets
Platform:
GPL1261
Series:
GSE62517
8 Samples
Download data: CEL
DataSet
Accession:
GDS5813
ID:
5813

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7.
Full record GDS5806

FLT3/ITD-SmoM2 acute myeloid leukemia model: sorted bone marrow cells

Analysis of KSL and GMP cells isolated from bone marrow of Flt3/ITD-SmoM2 transgenics at around 3 months of age when they developed leukemia. Wild-type and FLT3/ITD littermates of the FLT3/ITD-SmoM2 animals were also examined. Results provide insight into the role of SmoM2 in leukemic progression.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type, 3 genotype/variation sets
Platform:
GPL1261
Series:
GSE67134
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5806
ID:
5806

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

8.
Full record GDS5455

Ribosomal S6 kinase 2 deficiency effect on TNF-α transgenic model of inflammatory arthritis: fibroblast-like synoviocytes

Analysis of primary fibroblast-like synoviocytes from human tumor necrosis factor-α transgenics (hTNFtg) knocked out for ribosomal S6 kinase (Rsk2). Rsk2 belongs to the p90(RSK) family of serine/threonine kinases. Results provide insight into the role of Rsk2 in TNF-induced synovial hyperplasia.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE52992
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5455
ID:
5455

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9.
Full record GDS5451

Pregnancy effect on liver of cytochrome P450 2D6 hepatic metabolism model: time course

Analysis of livers of Cytochrome P450 2D6 (CYP2D6)-humanized mice at various gestational stages: pre-pregnancy, 21 days of pregnancy, and 7 days postpartum. Results provide insight into molecular mechanisms underlying increased CYP2D6-mediated drug metabolism during pregnancy.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 development stage sets
Platform:
GPL1261
Series:
GSE50166
6 Samples
Download data: CEL
DataSet
Accession:
GDS5451
ID:
5451

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

10.
Full record GDS5460

Survival motor neuron deficiency effect on axonal compartment of cultured motoneurons

Analysis of the axonal compartment of cultured motoneurons depleted for survival motor neuron (Smn). Smn is the protein deficient in spinal muscular atrophy (SMA). Results provide insight into the axonal mRNA content of degenerating motoneurons in vitro.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 genotype/variation sets
Platform:
GPL1261
Series:
GSE59506
9 Samples
Download data: CEL
DataSet
Accession:
GDS5460
ID:
5460

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

11.
Full record GDS5459

Survival motor neuron deficiency effect on somatodendritic compartment of cultured motoneurons

Analysis of the somatodendritic compartment of cultured motoneurons depleted for survival motor neuron (Smn). Smn is the protein deficient in spinal muscular atrophy (SMA). Results provide insight into the somatodendritic mRNA content of degenerating motoneurons in vitro.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 genotype/variation sets
Platform:
GPL1261
Series:
GSE59506
9 Samples
Download data: CEL
DataSet
Accession:
GDS5459
ID:
5459

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

12.
Full record GDS5458

Onecut1 deficiency effect on embryonic E14.5 retina

Analysis of embryonic retinas from onecut1 (OC1) knockouts at E14.5 and from wild type littermates. OC1 is a member of the Onecut family of transcription factors characterized by a cut domain and an atypical homeodomain. Results provide insight into the role of OC1 in the retina.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE57917
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5458
ID:
5458

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

13.
Full record GDS5457

Onecut2 deficiency effect on adult retina

Analysis of adult retinas from onecut2 (OC2) knockouts and wild type littermates. OC2 is a member of the Onecut family of transcription factors characterized by a cut domain and an atypical homeodomain. Results provide insight into the role of OC2 in the retina.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE57918
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5457
ID:
5457

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

14.
Full record GDS5468

Interleukin-33 effect on dual-specificity phosphatase 5-deficient bone marrow derived eosinophils

Analysis of BM-derived eosinophils isolated from dual-specificity phosphatase 5-deficient mice and stimulated with IL-33. DUSP5 is a growth factor‐inducible phosphatase preferentially expressed in immune cells. Results provide insight into the role of DUSP5 in IL-33 signaling in eosinophils.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE62999
20 Samples
Download data: CEL
DataSet
Accession:
GDS5468
ID:
5468

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

15.
Full record GDS5437

Metastatic breast cancer model: premetastatic lung

Analysis of premetastatic lung from BALB/c mice without any tumors (naïve) and from mice bearing nonmetastatic (67NR) or metastatic (4T1) breast carcinomas. Results provide insight into metastatic tumor-induced molecular changes in premetastatic lungs before the arrival of metastatic tumor cells.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL1261
Series:
GSE62817
14 Samples
Download data: CEL
DataSet
Accession:
GDS5437
ID:
5437

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

16.
Full record GDS5433

Articular cartilage zones: 1-week old normal proximal tibia

Analysis of superficial (SZ), intermediate/deep (IDZ), and resting (RZ) zones microdissected from articular cartilage of the proximal tibiae of 1-week old mice. Results provide insight into the spatial regulation of gene expression in articular cartilage.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 tissue sets
Platform:
GPL1261
Series:
GSE51994
14 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS5433
ID:
5433

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17.
Full record GDS5274

Alopecia areata model: skin

Analysis of alopecic skin from C3H/HeJ animals. The C3H/HeJ strain develops spontaneous alopecia areata (AA) with high similarity to human AA. AA is an autoimmune disease resulting from damage of hair follicle by T cells. Results provide insight into molecular mechanisms underlying AA pathogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL1261
Series:
GSE45513
6 Samples
Download data: CEL
DataSet
Accession:
GDS5274
ID:
5274

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18.
Full record GDS5273

Topical protein tyrosine kinase inhibitor effect on graft model of alopecia areata: time course

Analysis of skin from C3H/HeJ grafted recipients with established alopecia areata (AA) following alopecic graft transplantation that were treated with topical Janus kinase (JAK) inhibitor ruxolitinib or tofacitinib for up to 24 wks. Results provide insight into molecular basis of AA pathogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 agent, 4 time sets
Platform:
GPL1261
Series:
GSE45514
31 Samples
Download data: CEL
DataSet
Accession:
GDS5273
ID:
5273

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19.
Full record GDS5374

Histone/protein acetyltransferase (HAT) deficiency effect on Foxp3+ T-regulatory cells

Analysis of CD4+CD25+ T regulatory (Treg) cells from C57Bl/6 mice deficient in p300 or CBP (a p300 paralog). p300 and CBP are histone/protein acetyltransferases (HATs). Results provide insight into mechanisms by which HATs affect Treg biology.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 genotype/variation sets
Platform:
GPL1261
Series:
GSE60318
9 Samples
Download data: CEL
DataSet
Accession:
GDS5374
ID:
5374

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

20.
Full record GDS5608

NF-κB subunit p65 depletion effect on Ras-induced transformation model: cultured embryonic fibroblasts

Analysis of p65+/+Ras and p65-/-Ras cells generated by infecting NF-κB subunit p65+/+ and p65-/- MEFs with pBabe-HRASG12V. Post-injection of the Ras cells into SCID mice, RasT tumors were removed, reconstituted in culture and examined. Results provide insight into role of NF-κB in tumorigenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell line, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE59545
4 Samples
Download data: CEL, DCP, TXT
DataSet
Accession:
GDS5608
ID:
5608

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

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