GPL27885[Accession] - GEO DataSets

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Select item 2002436631.

Mucosal and systemic antigen-specific antibody responses correlate with protection against active tuberculosis in nonhuman primates

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Macaca fascicularis; synthetic construct; Homo sapiens

Type:: Protein profiling by protein array; Other

Platforms:: GPL30414 GPL33775 GPL27885
1258 Samples

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Series

Accession:: GSE243663

ID:: 200243663

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2002436572.

Mucosal and systemic antigen-specific antibody responses correlate with protection against active tuberculosis in nonhuman primates (LAM30 IgM)

(Submitter supplied) Increasing evidence supports a role ofthat antibodies in thecan defense protect against active tuberculosis (TB) but knowledge of potentially protective antigens, especially at in the mucosal airways level, is limited. The main objective of this study was to identify antigen-specific airway and systemic immunoglobulin isotype responses that were associated with the outcome of controlled latent Mycobacterium tuberculosis (Mtb) infection (LTBI) compared to uncontrolled infection (TB) in nonhuman primates. more...

Organism:: Homo sapiens; Macaca fascicularis

Type:: Protein profiling by protein array

Platform:: GPL27885
196 Samples

Download data: XLSX

Series

Accession:: GSE243657

ID:: 200243657

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001416793.

Capsular glycan recognition provides antibody-mediated protection against tuberculosis

(Submitter supplied) Increasing evidence suggests that antibodies (Abs) can have protective roles in M. tuberculosis (Mtb) infection but knowledge of the most relevant protective antigens and epitopes in humans is limited. Using novel glycan arrays, we establish that human serum IgG induced against the M. tuberculosis (Mtb) capsular polysacharide arabinomannan (AM) in natural Mtb infection is highly heterogeneous in its binding specificity and differs in both its reactivity to oligosaccharide (OS) motifs within AM and its functions between BCG vaccination and/or controlled (latent) versus uncontrolled (TB) M. more...

Organism:: Homo sapiens

Type:: Protein profiling by protein array

Platform:: GPL27885
24 Samples

Download data: MEV, XLSX

Series

Accession:: GSE141679

ID:: 200141679

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000278854.

LAM Subarray 30 - Antigens 10/22/2015

(Submitter supplied) NA - Synthetic antigens coupled to bovine serum albumin Protocol: Microarray slides were printed at Engineering Arts LLC (Phoenix, AZ). BSA conjugates were noncontact printed on Schott type E slides (Schott North America, Inc., Elmsford, NY) using an Engineering Arts au301 Rainmaker microarray printer and dispensed at 100 μg/mL in buffer (1:10 phosphate-buffered saline plus 0.005% vol/vol Triton X-100). more...