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Transcriptomic and functional deficits in human TREM2-/- microglia impair response to Alzheimer's pathology in vivo [bulk RNA-seq]
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Transcriptomic and functional deficits in human TREM2-/- microglia impair response to Alzheimer's pathology in vivo
PubMed Full text in PMC Similar studies
Transcriptomic and functional deficits in human TREM2-/- microglia impair response to Alzheimer's pathology in vivo [scRNA-seq]
Transcriptomic and functional deficits in human TREM2-/- microglia impair response to Alzheimer’s pathology in vivo [RNA-seq]
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The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases VI
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases V
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases IV
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases
PubMed Full text in PMC Similar studies Analyze with GEO2R
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases III
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases II
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases I
Prior activation state shapes the microglia response to anti-human TREM2 in a mouse model of Alzheimer's disease
TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease
Trem2 effects on brain resident myeloid cells in PS2APP model
Expression data of iPS microglia treated with TREM2 agonist antibody
Off target expression data from iPSC derived microglia treated with APOE/TREM2 ASOs for 24h/48h. The iPSC cells are from a wild type donor (BIONi10C).
Alzheimer’s disease neuroinflammatory risk genes can be targeted with RNase-H active antisense oligonucleotides in human microglia
TREM2 regulates microglial lipid metabolism during aging in mice [RNA-Seq]
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TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge
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TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge [single-cell RNA-Seq]
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