Osr2 functions as a mechanical checkpoint to augment CD8+ T cell exhaustion [Osr2OE_vs_Vector_CutnTag_CD8]

Single-cell or nucleus RNAseq of neuroblastoma patient-derived xenografts

Autophagy engaging and non-engaging hematopoietic stem cells

AThi oHSC ATlo oHSC WES - Identifying clonal differences or differences in mutation burden between autophagy engaging and non-engaging hematopoietic stem cells during mouse aging.

yHSC AThi oHSC ATlo oHSC ATAC-Seq - Differences in Chromatin Accessibility in Autophagy engaging vs non-autophagy engaging old hematopoeitic stem cells (HSC) comapred to young HSC.

yHSC AThi oHSC ATlo oHSC Bulk RNA-seq - Understanding transcriptional changes between autophagy engaging and non-engaging hematopoietic stem cells during mouse aging.

yHSC and oHSC scRNAseq with oHSC AThi ATlo Index Sorting. Assessing the transcriptional changes associated with autophagy engagement in old hematopoietic stem cells at single cell resolution.

yHSC and oHSC 10X scRNAseq under ad lib, fasted, or fast refeed conditions to evaluate transcriptional impact of transient autophagy engagement in hematopoietic stem cells.

RNA-seq analysis of B cells cultured with LPS and IL-12 and/or IFN gamma

TLR2 in γδ T cells is required for metabolic support of IL-17A ocular mucosal immune response to a commensal bacterium [ATAC-seq]

TLR2 in γδ T cells is required for metabolic support of IL-17A ocular mucosal immune response to a commensal bacterium [RNA-seq]

TLR2 in γδ T cells is required for metabolic support of IL-17A ocular mucosal immune response to a commensal bacterium

FOXO-regulated Deaf1 controls muscle regeneration through autophagy

A Japanese herbal medicine, Hochuekkito (TJ-41), has anti-inflammatory effects on the COPD mouse model

CPEB3 Maintains Developmental Competence of the Oocyte

Olfactory neuroblastoma mimics molecular subtypes and lineage trajectories of small cell lung cancer [Single cell RNA seq on RPM and RPMA GBC-derived allograft tumors, CellTagged]

Olfactory neuroblastoma mimics molecular subtypes and lineage trajectories of small cell lung cancer [Single cell RNA seq on RPM-GFP and RPMA ONB tumors]

Olfactory neuroblastoma mimics molecular subtypes and lineage trajectories of small cell lung cancer

Generation and characterization of mature hepatocyte organoids for liver metabolic studies

Knockout mice with pituitary malformations help identify human cases of hypopituitarism