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Series GSE104177 Query DataSets for GSE104177
Status Public on Sep 26, 2017
Title Global modulation of signaling pathways by SARM RAD140 in AR/ER+ breast cancer xenografts
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary These data demonstrates the regulation of AR and ER pathways by the SARM RAD140 and suggested a unique mechanism of action of RAD140 via the AR-mediated transcription repression.
Overall design HBCx-22 PDX were treated with RAD140 or vehicle and snap frozen tumor samples were subjected to RNA-seq analysis at the end of the study
Contributor(s) Wang D, He S, Yu Z
Citation(s) 28974548
Submission date Sep 25, 2017
Last update date May 15, 2019
Contact name ZiYang Yu
Phone 617-551-4065
Organization name Radius Health
Street address 950 Winter Street
City Waltham
State/province MA
ZIP/Postal code 02451
Country USA
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (6)
GSM2791399 HBCx-22 PDX treated with vehicle #1
GSM2791400 HBCx-22 PDX treated with vehicle #2
GSM2791401 HBCx-22 PDX treated with vehicle #3
BioProject PRJNA411985
SRA SRP118776

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Supplementary file Size Download File type/resource
GSE104177_comparison2_genes.summary.xlsx 8.4 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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