|
| Status |
Public on Dec 22, 2018 |
| Title |
Primary mid-trimester and term human cytotrophoblast, untreated [RNA-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We detected a genome-wide differential gene enrichment between mid-trimester and term human placenta. Pathway analysis identified that cytokine-cytokine receptor interaction, NF-κB, and TNF are the leading pathways enriched in term placenta. Our analysis has provided the first-time characterization of the key players of human placental origin with molecular changes across pregnancy, which could drive human labor.
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| |
|
| Overall design |
Total RNAs were extracted from 4 individual placentas at either mid-trimester or term pregnancy with use of Trizol method.
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| |
|
| Contributor(s) |
Wang B |
| Citation(s) |
30642670 |
| Submission date |
Dec 21, 2018 |
| Last update date |
Mar 20, 2019 |
| Contact name |
Bingbing Wang |
| E-mail(s) |
wangbi@rwjms.rutgers.edu
|
| Organization name |
Rutgers RWJMS
|
| Street address |
125 Paterson St Room 2143
|
| City |
New Brunswick |
| State/province |
New Jersey |
| ZIP/Postal code |
08901 |
| Country |
USA |
| |
|
| Platforms (1) |
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| Samples (8)
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|
| Relations |
| BioProject |
PRJNA511458 |
| SRA |
SRP174220 |
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