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| Status |
Public on Jan 20, 2021 |
| Title |
Gene expression profile of brain and hippocampus of B-cell sufficient and B-cell deficient 3xTgAD mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Brain and hippocampus gene expression was quantified in female and male 3xTgAD mice with and without B-cell deficiency as compared with sex- and age-matched B-cell sufficient (WT) and B-cell deficient (JHT) mice. (JHT)
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| Overall design |
Hippocampus (HIPP) and brain (BRAIN) tissue from male (N=6) and female (N=9) mice from four genotypes - wildtype mice (WT, C57BL/6j), triple-transgenic Alzheimer's Disease mouse model (3xTgAD), or a B cell knock-out genotype (JHT), and a JHT x 3xTgAD cross (JHT_3xTgAD)
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| Contributor(s) |
Kim K, Ragonnaud E, Bodogai M, Lehrmann E, Biragyn A |
| Citation(s) |
33846335 |
| Submission date |
Jan 19, 2021 |
| Last update date |
Apr 21, 2021 |
| Contact name |
Supriyo De |
| Organization name |
NIA-IRP, NIH
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| Department |
Laboratory of Genetics and Genomics
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| Lab |
Computational Biology & Genomics Core
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| Street address |
251 Bayview Blvd
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| City |
Baltimore |
| State/province |
Maryland |
| ZIP/Postal code |
21224 |
| Country |
USA |
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| Platforms (1) |
| GPL13912 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version) |
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| Samples (30)
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| Relations |
| BioProject |
PRJNA693279 |
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