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| Status |
Public on Nov 15, 2010 |
| Title |
Exon-Level Expression Data from Primary B Cells, Early Proliferating EBV-infected B Cells and Lymphoblastoid Cell Lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Eptstein-Barr Virus, an oncogenic herpesvirus, infects and immortalizes human B cells in culture into indefinitely-proliferating LCLs. We examined the gene expression of primary B cells during the process of infection and growth transformation at the exon level to analyze early and late virus-induced changes in expression and exon usage.
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| |
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| Overall design |
4 samples each of total RNA were extracted from purified resting B Cells, sorted early-proliferating EBV infected cells, and monoclonal LCLs, for a total of 12. Human Exon Array 1.0 data was then RMA normalized and analyzed in XRay and GenePattern.
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| |
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| Contributor(s) |
Forte E, Tourigny JP, Luftig MA |
| Citation(s) |
21147465, 22855490 |
| Submission date |
Feb 04, 2010 |
| Last update date |
Jul 10, 2014 |
| Contact name |
Luftig Laboratory |
| E-mail(s) |
jpt9@duke.edu, micah.luftig@duke.edu, pavel.nikitin@gmail.com
|
| Phone |
9196683123
|
| Organization name |
Duke University
|
| Department |
MGM
|
| Lab |
Luftig Lab
|
| Street address |
220 CARL Bldg Duke U Med Center
|
| City |
Durham |
| State/province |
NC |
| ZIP/Postal code |
27710 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL5188 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA125707 |
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