|
| Status |
Public on Apr 12, 2024 |
| Title |
Integration of multisector molecular characterization into a personalized peptide vaccine approach for patients with newly diagnosed glioblastoma; Gene expression using NanoString CAR-T Characterization Panel |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
Incorporation of multisector sampling in glioblastoma increases the candidate pool of potentially targetable neoantigens that can be successfully developed into a peptide-based vaccine
|
| |
|
| Overall design |
Here, we report the results of the CAR-T Characterization Panel from three regions of primary human glioblastoma resected from Subject 3 before administration of a personalized, neoantigen-based vaccine plus poly-ICLC (NeoVax) and one post-NeoVax (subject completed the priming phase and two cycles of booster vaccinations) tumor biopsy.
|
| |
|
| Contributor(s) |
Dunn GP, Johanns TM, Miller KE, Garfinkle EA |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jul 21, 2023 |
| Last update date |
Apr 13, 2024 |
| Contact name |
Katherine E Miller |
| E-mail(s) |
katherine.miller@nationwidechildrens.org
|
| Organization name |
Nationwide Children's Hospital
|
| Department |
Institute for Genomic Medicine
|
| Street address |
700 Children's Dr.
|
| City |
Columbus |
| State/province |
OH |
| ZIP/Postal code |
43215 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL29417 |
NanoString nCounter CAR-T Characterization panel [NS_Hs_CART_v1.0] |
|
| Samples (4)
|
|
| This SubSeries is part of SuperSeries: |
|
| Relations |
| BioProject |
PRJNA997449 |
Less...
More...