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| Status |
Public on May 01, 2024 |
| Title |
SNP genotyping array of human naive pluripotent stem cells II |
| Organism |
Homo sapiens |
| Experiment type |
SNP genotyping by SNP array
Genome variation profiling by SNP array
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| Summary |
Human pluripotent stem cells have two major pluripotent states, primed and naive, and the heterogeneity among cell lines in each pluripotent state remains a major unresolved problem. We showed that the overexpression of H1FOO-DD, which has a short expression period by fusing the destabilized domain to the maternal-specific linker histone H1FOO, together with OCT4, SOX2, KLF4 and LMYC in human somatic cells improves the quality of reprogramming to primed and naive pluripotency.
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| Overall design |
Genomic DNA from the 30 samples were hybridized onto the Infinium OmniExpress24 v1.4 DNA Analysis Kit (Illumina), and intensities were scanned by iScan (Illumina) following the manufacturer’s protocol.
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| Contributor(s) |
Kunitomi A, Nomura M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jan 22, 2024 |
| Last update date |
May 01, 2024 |
| Contact name |
Akira Kunitomi |
| E-mail(s) |
akira.kunitomi@gladstone.ucsf.edu
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| Organization name |
The J. David Gladstone Institutes
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| Street address |
1650 Owens Street
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| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94158 |
| Country |
USA |
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| Platforms (1) |
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| Samples (30)
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| This SubSeries is part of SuperSeries: |
| GSE224850 |
H1FOO-DD promotes efficiency and uniformity in reprogramming to naive pluripotency |
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| Relations |
| BioProject |
PRJNA1067680 |
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