|
| Status |
Public on Jan 01, 2013 |
| Title |
Genome-wide maps of chromatin remodeler SNF5 in human pluripotent cells. |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We report the application of single-molecule-based sequencing technology for high-throughput profiling of SNF5 binding in human pluripotent embryonic carcinoma NCCIT and SNF5 overexpressed NCCIT cells. We generated genome-wide cSNF5 maps of NCCIT and SNF5 overexpressed NCCIT cells from chromatin immunoprecipitated DNA. SNF5 and OCT4 seem not to share their binding in OCT4 centered binding plot in control, while SNF5 overexpression directs SNF5 to OCT4 target genes.
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| |
|
| Overall design |
Examination of the relationship between SNF5 and OCT4 binding in control and SNF5 overexpressed cells.
|
| |
|
| Contributor(s) |
Jones P |
| Citation(s) |
23637628 |
| Submission date |
Feb 28, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
jueng soo You |
| Organization name |
USC
|
| Department |
Norris Comprehensive Cancer Center
|
| Lab |
Peter Jones
|
| Street address |
1441 Eastlake Ave
|
| City |
LA |
| State/province |
CA |
| ZIP/Postal code |
90042 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (5)
|
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| This SubSeries is part of SuperSeries: |
| GSE36140 |
SNF5 is an essential executor of epigenetic regulation in pluripotency and differentiation |
|
| Relations |
| SRA |
SRP011091 |
| BioProject |
PRJNA155795 |
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