|
| Status |
Public on May 31, 2013 |
| Title |
Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types (exon expression) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Custom Agilent 8 x 15K microarray interrogating exon level expression of a set of genes previously known to be involved in oncogenic rearrangements. The goal of this study was to discover novel gene fusions by screening for exonic expression transitions within individual genes.
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| |
|
| Overall design |
Sixteen cancer samples and cell lines, including eight positive controls with known gene fusions and eight sarcoma specimens, where gene fusions have yet to be discovered, were hybridized against a common reference mRNA control (pooled from 11 diverse cell lines)
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| |
|
| Contributor(s) |
Giacomini CP, Pollack JR |
| Citation(s) |
23637631 |
| Submission date |
Jul 12, 2012 |
| Last update date |
May 16, 2014 |
| Contact name |
Craig Patrick Giacomini |
| E-mail(s) |
cpg17@stanford.edu
|
| Organization name |
Stanford University
|
| Department |
Pathology
|
| Lab |
Jonathan Pollack (M.D./Ph.D.) Laboratory
|
| Street address |
269 Campus Drive (CCSR 3245A)
|
| City |
Stanford |
| State/province |
CA |
| ZIP/Postal code |
94305-5176 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL15797 |
Agilent-019738 Custom 8 X 15k Exon Microarray |
|
| Samples (16)
|
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| This SubSeries is part of SuperSeries: |
| GSE45137 |
Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types |
|
| Relations |
| BioProject |
PRJNA170480 |
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