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| Status |
Public on Aug 09, 2013 |
| Title |
KBM7 genetrap mutant cells stimulated with TNF-alpha and IFN-gamma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Transcriptional response of KBM7 cells to IFN-gamma or TNF-alpha was investigated in control or cells with genetrap insertions in JAK2 or TNFRS1A, respectively. The experiment shows that, as expected, cells lacking JAK2 or TNFRS1A expression display a severly blunted response to the tested cytokines.
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| Overall design |
KBM7 genetrap mutant cells stimulated with TNF-alpha and IFN-gamma
Sample WT_1 corresponds with the control sample for the IFN-gamma stimulation; Sample WT_2 corresponds with the control sample for the TNF-alpha stimulation.
As the expected differences between the samples was large, only single replicates were performed for each condition
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| Contributor(s) |
Nijman S, Buerckstuemmer T |
| Citation(s) |
24161985 |
| Submission date |
Jul 13, 2013 |
| Last update date |
Aug 23, 2018 |
| Contact name |
Sebastian M Nijman |
| E-mail(s) |
snijman@cemm.oeaw.ac.at
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| Organization name |
Research Center for Molecular Medicine
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| Lab |
Nijman
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| Street address |
Lazarettgasse 14
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| City |
Vienna |
| ZIP/Postal code |
1090 |
| Country |
Austria |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA211962 |
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