|
| Status |
Public on Dec 15, 2014 |
| Title |
A human integrin-α3 mutation confers major renal developmental defects. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Integrin-α3 plays a central role in the interplay of cells, morphogens and ECM, required for proper nephrogenesis, thus adding ITGA3 to the list of CAKUT (congenital anomalies of the kidney and urinary tract)-causing genes.
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| |
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| Overall design |
we used renal tissue originally obtained from a patient with an ITGA3 mutation and assessed its gene expression profile as compared to controls
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| |
|
| Contributor(s) |
Shukrun R, Vivante A, Pleniceanu O, Vax E, Anikster Y, Dekel B, Lotan D |
| Citation(s) |
24621570 |
| Submission date |
Jan 20, 2014 |
| Last update date |
Oct 25, 2022 |
| Contact name |
jasmine Jacob |
| E-mail(s) |
j-jacob@sheba.health.gov.il
|
| Phone |
0523790500
|
| Organization name |
Sheba Medical Center at Tel HaShomer
|
| Street address |
haChevel 33
|
| City |
Shoham |
| State/province |
-Select- |
| ZIP/Postal code |
60850 |
| Country |
Israel |
| |
|
| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA236572 |
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