|
| Status |
Public on Mar 02, 2015 |
| Title |
Differential susceptibility of human pleural and peritoneal mesothelial cells to asbestos exposure |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We hypothesize that the observed differences in incidences of pleural and peritoneal malignant mesothelioma (MM) are the result of differences in the direct response of these cell types to asbestos rather than to differences mediated by the in vivo microenvironment. To test this hypothesis, we characterized cellular responses to asbestos in a controlled environment using high-throughput RNA sequence and other assays.
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| |
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| Overall design |
Examination of asbestos-treated versus untreated mesothelial cells from four cell lines representing two tissue types in culture.
|
| |
|
| Contributor(s) |
Dragon JA, Shukla A |
| Citation(s) |
25757056 |
| Submission date |
Dec 08, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Julie Dragon |
| E-mail(s) |
julie.dragon@uvm.edu
|
| Organization name |
UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
|
| Department |
MMG
|
| Street address |
95 Carrigan Dr
|
| City |
Burlington |
| State/province |
VT |
| ZIP/Postal code |
05405 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL15433 |
Illumina HiSeq 1000 (Homo sapiens) |
|
| Samples (16)
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|
| Relations |
| BioProject |
PRJNA269624 |
| SRA |
SRP050954 |
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