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| Status |
Public on Apr 12, 2016 |
| Title |
Gene expression in liver of interleukin-18 knockout mice at 6 and 12 weeks of age |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Interleukin-18 knockout mice had metabolic syndromes after 24 weeks of age. We examined gene expression profiles in mice liver using genome-wide microarray technology, and compared gene expression profiles between wild-type and interleukin-18 knockout mice. To verify responsible molecules involved in metabolic syndromes such as obesity, we compared the gene expression levels at 6 and 12 weeks of age, and picked up them whose expression was more than 2-fold increase or less than 1/2-fold decrease.
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| Overall design |
The mouse whole livers derived from wild type and interleukin-18 knockout mice at 6 and 12 weeks of age were examined. Each strain was run in triplicate.
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| Contributor(s) |
Yamanishi K, Okuzaki D |
| Citation(s) |
27063959 |
| Submission date |
Dec 18, 2014 |
| Last update date |
Jul 19, 2017 |
| Contact name |
Daisuke Okuzaki |
| E-mail(s) |
dokuzaki@biken.osaka-u.ac.jp
|
| Phone |
+81-6-6879-4935
|
| Organization name |
Osaka univ.
|
| Department |
Immunology Frontier Research Center
|
| Lab |
Human Immunology （Single Cell Genomics)
|
| Street address |
Yamadaoka 3-1
|
| City |
Suita |
| State/province |
Osaka |
| ZIP/Postal code |
565-0871 |
| Country |
Japan |
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| Platforms (1) |
| GPL13912 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version) |
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| Samples (12)
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| GSM1568418 |
Liver_wild type_12w-biological rep1 |
| GSM1568419 |
Liver_wild type_12w-biological rep2 |
| GSM1568420 |
Liver_wild type_12w-biological rep3 |
| GSM1568421 |
Liver_interleukin-18 knockout_6w-biological rep1 |
| GSM1568422 |
Liver_interleukin-18 knockout_6w-biological rep2 |
| GSM1568423 |
Liver_interleukin-18 knockout_6w-biological rep3 |
| GSM1568424 |
Liver_interleukin-18 knockout_12w-biological rep1 |
| GSM1568425 |
Liver_interleukin-18 knockout_12w-biological rep2 |
| GSM1568426 |
Liver_interleukin-18 knockout_12w-biological rep3 |
|
| Relations |
| BioProject |
PRJNA270718 |
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