|
| Status |
Public on Jun 12, 2015 |
| Title |
Disease-Associated SNPs From non-Coding Regions in Juvenile Idiopathic Arthritis Are Located Within or Adjacent to Functional Genomic Elements of Human Neutrophils and CD4+ T Cells [ChIP-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We applied ChIP-Seq on two histone marks: H3K4me1 and H3K27ac in healthy human neutrophils. After peak calling, we obtained the peak regions enriched with H3K4me1 and H3K27ac histone marks and identifed aciive enhancers (H3K27ac+/H3K4me1+) and H3K27ac active enhancers (H3K27ac+/H3K4me1-) in human neutrophils and checked whether those enhancers are located in the LD blocks of 22 SNPs associtated with Juvenile Idiopathic Arthritis.
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| |
|
| Overall design |
Identification of active enhancers in human neutrohils
|
| |
|
| Contributor(s) |
Zhu L, Jiang K |
| Citation(s) |
25833190 |
| Submission date |
Mar 13, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Lisha Zhu |
| E-mail(s) |
lishazhu4508@gmail.com
|
| Organization name |
UT Health Science Center at Houston
|
| Street address |
7000 fannin st
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (9)
|
|
| This SubSeries is part of SuperSeries: |
| GSE66898 |
Disease-Associated SNPs From non-Coding Regions in Juvenile Idiopathic Arthritis Are Located Within or Adjacent to Functional Genomic Elements of Human Neutrophils and CD4+ T Cells |
|
| Relations |
| BioProject |
PRJNA278278 |
| SRA |
SRP056160 |
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