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| Status |
Public on Mar 25, 2016 |
| Title |
Fine-mapping of DNA modifications in the lactase gene region of humans and mice |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
Bisulfite padlock probe technique was used to examine DNA modifications at the lactase gene region for human and mouse tissues
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| |
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| Overall design |
DNA modifications were investigated in human sperm, blood, jejunal enterocytes and jejunum lacking enterocytes, as well as mouse jejunal enterocytes and jejunum lacking enterocytes. For WGA samples, a genome devoid of DNA modifications was used to verify the efficiency of the bisulfite conversion reactions (the tissue sources were human or mouse intestine).
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| |
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| Contributor(s) |
Petronis A, Labrie V, Buske OJ |
| Citation(s) |
27159559 |
| Submission date |
Jun 18, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Arturas Petronis |
| Organization name |
Centre for Addiction and Mental Health
|
| Street address |
250 College St Rm606
|
| City |
Toronto |
| ZIP/Postal code |
M5T 1R8 |
| Country |
Canada |
| |
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| Platforms (3) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (387)
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| This SubSeries is part of SuperSeries: |
| GSE69979 |
Epigenetics of lactose intolerance and lactase persistence |
|
| Relations |
| BioProject |
PRJNA287318 |
| SRA |
SRP059623 |
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