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| Status |
Public on Jan 04, 2017 |
| Title |
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In order to identify the effects of JNK inhibitor or p38 Inhibitor on the transcriptome of ATP7B H1069Q-overexpressing liver cells, we performed RNAseq experiments
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| Overall design |
Transcriptome analysis of the hepatocytes overexpressing ATP7B H1069Q, compared with hepatocytes overexpressing ATP7B WT.
Total RNA was extracted from HepG2 cells; RNA extracted from hepatocytes overexpressing ATP7B WT was used as control.
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| Contributor(s) |
Chesi G, Polishchuk RS |
| Citation(s) |
27714068 |
| Submission date |
Apr 18, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Annamaria Carissimo |
| E-mail(s) |
carissimo@tigem.it
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| Organization name |
Tigem
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| Street address |
via Castellino
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| City |
Napoli |
| ZIP/Postal code |
80131 |
| Country |
Italy |
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| Platforms (1) |
| GPL15433 |
Illumina HiSeq 1000 (Homo sapiens) |
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| Samples (12)
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| GSM2125267 |
HepG2 cells expressing ATP7B WT, biological rep1 |
| GSM2125268 |
HepG2 cells expressing ATP7B WT, biological rep2 |
| GSM2125269 |
HepG2 cells expressing ATP7B WT, biological rep3 |
| GSM2125270 |
HepG2 cells expressing ATP7B H1069Q, biological rep1 |
| GSM2125271 |
HepG2 cells expressing ATP7B H1069Q, biological rep2 |
| GSM2125272 |
HepG2 cells expressing ATP7B H1069Q, biological rep3 |
| GSM2125273 |
HepG2 cells expressing ATP7B H1069Q and treated with JNK Inhibitor, biological rep1 |
| GSM2125274 |
HepG2 cells expressing ATP7B H1069Q and treated with JNK Inhibitor, biological rep2 |
| GSM2125275 |
HepG2 cells expressing ATP7B H1069Q and treated with JNK Inhibitor, biological rep3 |
| GSM2125276 |
HepG2 cells expressing ATP7B H1069Q and treated with p38 MAPK Inhibitor, biological rep1 |
| GSM2125277 |
HepG2 cells expressing ATP7B H1069Q and treated with p38 MAPK Inhibitor, biological rep2 |
| GSM2125278 |
HepG2 cells expressing ATP7B H1069Q and treated with p38 MAPK Inhibitor, biological rep3 |
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| Relations |
| BioProject |
PRJNA318738 |
| SRA |
SRP073426 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE80361_RAW.tar |
2.6 Mb |
(http)(custom) |
TAR (of TXT) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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