|
| Status |
Public on Jun 14, 2016 |
| Title |
Genome-wide KDM5A occupancy after MK2206/DMSO treatment of T47D cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We perfomed ChIP-seq using KDM5A antibodies in T47D cells after 24 hour treatment with the AKT inhibitor MK2206 or DMSO. We show that the cistrome of the H3K4 demethylase KDM5A is affected by AKT inhibition.
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| |
|
| Overall design |
Comparison of genome-wide KDM5A binding after AKT inhibition vs vehicle
|
| |
|
| Contributor(s) |
Dreijerink K, Groner A, Spangle J |
| Citation(s) |
27292631 |
| Submission date |
Apr 22, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Koen M.A. Dreijerink |
| E-mail(s) |
koendreijerink@yahoo.com
|
| Organization name |
Dana-Farber Cancer Institute
|
| Department |
Medical Oncology
|
| Street address |
450 Brookline Avenue
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (2) |
|
| This SubSeries is part of SuperSeries: |
| GSE80594 |
PI3K/AKT signaling regulates H3K4 methylation in breast cancer |
|
| Relations |
| BioProject |
PRJNA319400 |
| SRA |
SRP073744 |
