|
| Status |
Public on Nov 05, 2004 |
| Title |
Targets of HNF1b, HNF4a2 and HNF6 in INS-1 cells |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors HNF1b, HNF4a2, and HNF6 (onecut1) were identified.
Two different clones containing the same transcription factor were analyzed in the non-induced and tet-induced (24 h) state.
Keywords: ordered
|
| |
|
| |
|
| Contributor(s) |
Thomas H, Senkel S, Erdmann S, Arndt T, Turan G, Klein-Hitpass L, Ryffel GU |
| Citation(s) |
15520459 |
| Submission date |
Jul 23, 2004 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Ludger Klein-Hitpass |
| E-mail(s) |
ludger.klein-hitpass@uni-essen.de
|
| Phone |
+49 201 723 85552
|
| Organization name |
Institut fuer Zellbiologie
|
| Department |
Universitaetsklinikum
|
| Lab |
BioChip Lab
|
| Street address |
Virchowstr. 173
|
| City |
Essen |
| ZIP/Postal code |
D-45122 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL341 |
[RAE230A] Affymetrix Rat Expression 230A Array |
|
| Samples (12)
|
|
| This SubSeries is part of SuperSeries: |
| GSE6428 |
HNF1b, HNF4a2 and HNF6 targets |
|
| Relations |
| BioProject |
PRJNA104741 |
Less...
More...